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About 5% of the population of the United States regularly uses at least one Benzodiazepine.

The percentages of American students who reported drinking alcohol fell in 2018, with 8% of 8th graders, 18% of 10th graders, and 30% of 12th graders reporting alcohol consumption in the previous month.  By contrast, 10% of 8th graders, 25% of 10th graders, and 39% of 12th graders in 2013 reported drinking alcohol within the previous month.

The percentage of Cocaine-related fatal overdoses increased by 34% from 2016 to 2017.

In 2017, 34.2 million Americans operated a vehicle under the influence of alcohol or drugs.

Benzodiazepine dependence often coincides with other forms of substance abuse. For example, about 20% of Americans with alcoholism also abuse Benzodiazepines.

In 2017, 26% of Americans aged 18 years or older admitted to binge drinking in the past month.